Human SELPLG / PSGL-1 / CD162 Protein (Recombinant Fc, C-terminus)
Product Sizes
1 mg
£ POA
LS-G137856-1MG
10 ug
£ POA
LS-G137856-10UG
50 ug
£ POA
LS-G137856-50UG
500 ug
£ POA
LS-G137856-500UG
About this Product
- SKU:
- LS-G137856
- Additional Names:
- SELPLG, CD162 antigen, CLA, CD162, PSGL1, PSGL-1, Selectin P ligand
- Buffer:
- Lyophilized from a sterile solution in 20 mM Tris, pH 8.0, 150 mM NaCl
- Extra Details:
- PSGL-1 (CD162), is a mucintype glycoprotein that plays a key role in leukocyte adhesion. Human PSGL-1 cDNA encodes 412 amino acids (aa). It expressed on neutrophils, monocytes and most lymphocytes. The mature PSGL-1 (aa 42-412) is expressed as a disulfide-linked homodimer that signals intracellularly and promotes integrin activation. PSGL-1 is found on virtually all leukocytes, dendritic cells, platelets, and some endothelial cells. It is primarily responsible for early events in extravasation, especially rolling adhesion of leukocytes to vascular endothelium. Through high affinity, This SLe(x)-type proteoglycanPGSL-1 calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation.
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- 2-8[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles., RT Aliquot. Avoid freeze/thaw cycles., -20[o]C reconstituted. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:137856
