Human TNFRSF1A / TNFR1 Protein (Recombinant)
Product Sizes
20 ug
£ POA
LS-G133847-20UG
5 ug
£ POA
LS-G133847-5UG
About this Product
- SKU:
- LS-G133847
- Additional Names:
- TNFRSF1A, CD120a, CD120a antigen, MS5, p60, TBP1, TNF-R55, TNFAR, TNFR1, p55-R, TNF-R, TNF-R-I, TNF-R1, TNF-RI, Tnfr, TNFR-I, TNFR1-d2, TNFR60, FPF, p55, Tbpi, TNFR55
- Buffer:
- Lyophilized
- Extra Details:
- TNFRI belongs to the TNFR superfamily of transmembrane proteins, and is expressed in most cell types. Binding of either TNF-a or TNF-B Beta to TNFRI initiates a signal transduction pathway that results in the activation of the transduction factor NF-?B, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis. Soluble TNF Receptor I (sTNFRI) is capable of inhibiting TNF-a and TNF-B Beta activities by acting as a decoy receptor that serves as a sink for the TNF ligands. The human TNFRI gene encodes for a 455 amino acid type I transmembrane protein, which contains a 21 amino acid signal sequence, a 190 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 221 amino acid cytoplasmic domain. Recombinant Human sTNF Receptor Type I is an 18.3 kDa protein (162 amino acid residues) comprising the cysteine-rich, ligand-binding portion of the extracellular domain of the TNFRI protein.
- Molecular Weight:
- 18.3 kDa
- Physical State:
- Lyophilized
- Purity:
- >98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles. Desiccated.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:133847
