Human IL35 Protein (Recombinant)
Product Sizes
10 ug
£ POA
LS-G133801-10UG
2 ug
£ POA
LS-G133801-2UG
About this Product
- SKU:
- LS-G133801
- Additional Names:
- IL35
- Buffer:
- Sterile filtered through a 0.2-micron filter. Lyophilized from 10mM Sodium Phosphate, pH 7.4 + 500mM NaCl + 0.5% CHAPS
- Extra Details:
- Interleukin-35 is a glycosylated, heterodimeric protein consisting of the p35 subunit from IL-12 (IL-12a) and the B Beta subunit from IL-27 (EBI3). IL-35 can be expressed by regulatory T-cells (Tregs), macrophages, and certain trophoblast and dendritic cells. It is induced in response to inflammation, and generally acts as an inflammation suppressor. IL-35 suppresses inflammation by exerting multiple activities, including the induction of regulatory T-cells and the suppression of Th17 cells. Recombinant Human IL-35 produced from HEK293 cells is a glycosylated protein, primarily heterodimeric, that migrates as a diffuse band centered at an apparent molecular weight of about 60 kDa by SDS-PAGE analysis under non-reducing conditions. Recombinant Human IL-35 expressed in HEK293 cells contains 406 amino acid residues and has a calculated molecular weight of 45.8 kDa.
- Molecular Weight:
- 60 kDa or 45.8 kDa
- Physical State:
- Lyophilized
- Purity:
- >90%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles. Desiccated.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:133801
