Human Soluble Interleukin 4 Receptor Alpha (sIL4Ra) Protein (Recombinant)
Product Sizes
20 ug
£ POA
LS-G133798-20UG
5 ug
£ POA
LS-G133798-5UG
About this Product
- SKU:
- LS-G133798
- Buffer:
- Lyophilized
- Extra Details:
- IL-4 can signal through type I and type II receptor complexes, which share a common gamma chain (?c). The type I receptor contains, in addition to the ?c, an IL-4Ra subunit, whereas the type II receptor contains the IL-13Ra. The secreted extracellular domain of IL-4Ra, called sIL-4Ra, binds IL-4 and antagonizes its activity. It plays an important role in regulating the differentiation of naive CD4+ T cells and class switching to IgG1 and IgE. PeproTech's CHO cell-derived Recombinant Human sIL-4 Receptor a is a 23.9 kDa glycoprotein corresponding to 209 amino acid residues of the extracellular domain of IL-4Ra. As a result of glycosylation, Recombinant Human sIL-4 Receptor a migrates with an apparent molecular mass of approximately 50-65 kDa by SDS-PAGE gel, under reducing conditions.
- Molecular Weight:
- 23.9 kDa or 50-65 kDa
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles. Desiccated.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:133798
