Mouse Activin A Protein (Recombinant)
Product Sizes
10 ug
£ POA
LS-G133783-10UG
2 ug
£ POA
LS-G133783-2UG
About this Product
- SKU:
- LS-G133783
- Buffer:
- Lyophilized
- Extra Details:
- Activin A is a TGF-B Beta family member that exhibits a wide range of biological activities, including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-B Beta antagonist, follistatin. Activin A binds to the two forms of activin receptor type I (Act RI-A and Act RI-B) and two forms of activin receptor type II (Act RII-A and Act RII-B). Activins are homodimers or heterodimers of different B Beta subunits. They are produced as precursor proteins with an amino terminal propeptide that is cleaved to release the C-terminal bioactive ligand. Recombinant Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two B BetaA chains, each containing 116 amino acid residues.
- Molecular Weight:
- 26.0 kDa
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles. Desiccated.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:133783
