Human BMP2 Protein (Recombinant)
Product Sizes
10 ug
£ POA
LS-G133782-10UG
2 ug
£ POA
LS-G133782-2UG
About this Product
- SKU:
- LS-G133782
- Additional Names:
- BMP2, BDA2, BMP-2, BMP-2A, BMP2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A
- Buffer:
- Lyophilized
- Extra Details:
- BMPs (Bone Morphogenetic Proteins) belong to the TGF-B Beta superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with an osteoconductive carrier such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 appears to play an important role in cardiac morphogenesis, and is expressed in a variety of other tissues, including lung, liver, spleen, prostate, ovary, and small intestine. The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains (monomers) linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease. Recombinant Human/Murine/Rat BMP-2 derived from CHO cells is a homodimeric glycoprotein that consists of two 114 amino acid polypeptide chains linked by a single disulfide bond. Due to glycosylation, CHO cell-derived Human/Murine/Rat BMP-2 migrates at an apparent molecular weight of approximately 28-29 kDa by SDS-PAGE analysis under non-reducing conditions.
- Molecular Weight:
- 26 kDa or 28-29 kDa
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles. Desiccated.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:133782
