Human TNFRSF12A / TWEAK Receptor Protein (Recombinant)
Product Sizes
1 mg
£ POA
LS-G131449-1MG
100 ug
£ POA
LS-G131449-100UG
25 ug
£ POA
LS-G131449-25UG
About this Product
- SKU:
- LS-G131449
- Additional Names:
- TNFRSF12A, CD266 antigen, CD266, FGF-inducible 14, FN14, Tweak-receptor, TWEAKR
- Buffer:
- Lyophilized from Sterile Solution PBS
- Extra Details:
- Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) is the receptor for TNFSD12/TWEAK and is the smallest member of the TNF receptor superfamily. It is composed of a signal peptide, an extracellular domain, a membrane-anchoring domain, and a cytoplasmic "death" domain, which can activate a cell's apoptotic mechanisms. It also promotes endothelial cell proliferation and angiogenesis, and modulates cellular adhesion to matrix proteins. TNFRSF12A expression can be found in the spleen, thymus, small intestine, and colon, and can be activated by membrane-anchored or soluble versions of TWEAK.
- Molecular Weight:
- ~5.6 kDa
- Physical State:
- Lyophilized
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -70[o]C lyophilized. Avoid freeze/thaw cycles., 2-8[o]C reconstituted. Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
- Manufacturer's Data Sheet:131449
