CD80 Antibody (clone IDEC-114)
Product Sizes
0.2 mg
£ POA
LS-C821452-0.2MG
About this Product
- SKU:
- LS-C821452
- Additional Names:
- CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 molecule, CTLA-4 counter-receptor B7.1
- Application:
- Block/Inhibit/Neutralise, Cell-based/Functional Assay, ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, 0.02% Proclin 300
- translate.label.attr.clone:
- IDEC-114
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1 mg/ml
- Host:
- Rabbit
- Immunogen:
- Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen. The variable regions of the light and heavy chains were then cloned by being incorporated into a cassette vector (N5LG1) containing human constant region genes and subsequently transfected into the Dg44 CHO cell line (Hariharan K, 2013)
- Isotype:
- IgG, lambda
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- Galiximab is a primatized mAb which consists of human constant and primate (cynomolgus macaque) variable regions and binds specifically to CD80. CD80 is a surface glycoprotein and a member of the B7 family of costimulatory molecules. CD80 antigen regulates T cell activation (through interacting with CD28 or CD152) and is expressed transiently in antigen-presenting cells, T cells and normal B cells
- Storage Conditions:
- 2-8[o]C Aliquot. Store undiluted., -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Recombinant Antibodies
- Manufacturer's Data Sheet:848156
