C5b-9 Terminal Complement Complex / TCC Antibody (clone 3R2/0)
Product Sizes
0.1 mg
£ POA
LS-C58185-0.1MG
About this Product
- SKU:
- LS-C58185
- Application:
- ELISA, Flow Cytometry, IHC-Frozen, Immunohistochemistry, Western Blot
- Buffer:
- BBS, 0.1% Sodium Azide
- translate.label.attr.clone:
- 3R2/0
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Host:
- Mouse
- Isotype:
- IgG2a
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- Recognizes the SC5b-9 complex of around 330 kD. Both the classical and alternative complement pathways result in the formation of the cytolysis inducing C5b-9 complex. This complex is composed of 190 kD C5b which is bound to cells via 71 kD C9. Sublytic assembly of C5b-9 on plasma membranes induces cell cycle activation and survival. The binding of C5b-9 to the 75 kD S-protein (or vitronectin) in
- Storage Conditions:
- 2[o]C to 8[o]C or -20[o]C Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:58655
