APAF1 / APAF-1 Antibody (HRP)
Product Sizes
100 ul
£ POA
LS-C543511-100UL
About this Product
- SKU:
- LS-C543511
- Additional Names:
- APAF1, APAF-1, CED4, KIAA0413
- Application:
- Western Blot
- Buffer:
- PBS, pH 7.2
- Clonality:
- Polyclonal
- Conjugate:
- HRP
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to amino acids 12-28 of human Apaf1.
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Human, Mouse, Nematode, Other Mammal
- Shipping Conditions:
- Ambient
- Specificity:
- Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. Recognizes a 130kD band in Western blots. Species cross-reactivity
- Storage Conditions:
- 2-8[o]C
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:557073
