FBXO3 Antibody
Product Sizes
100 ug
£ POA
LS-C502157-100UG
50 ug
£ POA
LS-C502157-50UG
About this Product
- SKU:
- LS-C502157
- Additional Names:
- FBXO3, F-box protein 3, F-box protein FBX3, F-box only protein 3, FBA, FBX3
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry
- Buffer:
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Clonality:
- Polyclonal
- Concentration:
- 4 mg/ml
- Host:
- Rabbit
- Immunogen:
- Recombinant Human F-box only protein 3 protein (276-376AA)
- Isotype:
- IgG
- Purification:
- Protein G Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Ambient
- Specificity:
- Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:515671
