AXIN1 / Axin-1 Antibody
Product Sizes
100 ug
£ POA
LS-C500625-100UG
50 ug
£ POA
LS-C500625-50UG
About this Product
- SKU:
- LS-C500625
- Additional Names:
- AXIN1, Axis inhibitor 1, AXIN, Axin 1, Axis inhibition protein 1, Fused, mouse, homolog of, HAxin, PPP1R49, Axin-1
- Application:
- ELISA
- Buffer:
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Clonality:
- Polyclonal
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Axin-1 protein (418-707AA)
- Isotype:
- IgG
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signal
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:514139
