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Antibodies

ITGB4 / Integrin Beta 4 Antibody

Product Sizes
100 ug
£ POA
LS-C499158-100UG
50 ug
£ POA
LS-C499158-50UG
About this Product
SKU:
LS-C499158
Additional Names:
ITGB4, CD104, Integrin beta-4, Integrin Beta 4, gp150, CD104 antigen, Integrin beta-4 subunit, Integrin, beta 4
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Clonality:
Polyclonal
Concentration:
3.5 mg/ml
Host:
Rabbit
Immunogen:
Recombinant Human Integrin beta-4 protein (1401-1533AA)
Isotype:
IgG
Purification:
Protein G Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Ambient
Specificity:
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351
Storage Conditions:
-70[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:
LifeSpan Biosciences
Type:
Antibody: Polyclonal Antibody
  • Manufacturer's Data Sheet:512672
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