IER3 / IEX-1 Antibody (Biotin)
Product Sizes
100 ug
£ POA
LS-C499094-100UG
50 ug
£ POA
LS-C499094-50UG
About this Product
- SKU:
- LS-C499094
- Additional Names:
- IER3, DIF-2, DIF2, Gly96, mouse, homolog of, IEX1, IEX-1L, Immediate early protein GLY96, Immediate early response 3, Immediately early gene X-1, GLY96, IEX-1, Protein DIF-2, Protein PRG1, PRG1, Anti-death protein
- Application:
- ELISA
- Buffer:
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Clonality:
- Polyclonal
- Conjugate:
- Biotin
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Radiation-inducible immediate-early gene IEX-1 protein (1-82AA)
- Isotype:
- IgG
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:512608
