AIM2 Antibody
Product Sizes
100 ug
£ POA
LS-C498354-100UG
50 ug
£ POA
LS-C498354-50UG
About this Product
- SKU:
- LS-C498354
- Additional Names:
- AIM2, Absent in melanoma 2, PYHIN4
- Application:
- ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
- Buffer:
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Clonality:
- Polyclonal
- Host:
- Rabbit
- Immunogen:
- Recombinant human Interferon-inducible protein AIM2 protein (81-326AA)
- Isotype:
- IgG
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origi
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:511868
