Complement C3c Antibody (clone 10-02A)
Product Sizes
0.1 mg
£ POA
LS-C44974-0.1MG
About this Product
- SKU:
- LS-C44974
- Application:
- ELISA, Flow Cytometry, IHC-Frozen, Immunohistochemistry, Western Blot
- Buffer:
- BBS, 0.1% Sodium Azide
- translate.label.attr.clone:
- 10-02A
- Clonality:
- Monoclonal
- Concentration:
- 1.2 mg/ml
- Host:
- Mouse
- Immunogen:
- Native human C3 from normal serum, highly purified by chromatography.
- Isotype:
- IgG1
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- Recognizes 135kD complement component 3c (C3c), present in blood serum. C3c is generated over the course of complement activation, where convertase C4b2a (classical pathway) and convertase C3bBb (alternative pathway) cleave C3 to C3b and C3a. C3b is further degraded into iC3b and C3dg/C3d. iC3b is then slowly cleaved (possibly by factor I) to form C3c (beta chain + alpha chain fragment 1 + alpha c
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles., 2-8[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:44712
