APP / Beta Amyloid Precursor Antibody (C-Terminus)
Product Sizes
0.1 mg
£ POA
LS-C42820-0.1MG
About this Product
- SKU:
- LS-C42820
- Additional Names:
- APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II
- Application:
- IHC-Paraffin, Western Blot
- Buffer:
- PBS, 0.02% Sodium Azide
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to amino acids 737-751 of human APP (C-TERMINAL).
- Isotype:
- IgG
- Purification:
- Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Ambient
- Specificity:
- Recognizes both intact Amyloid Precursor Protein (APP), and also the C99 fragment generated by Beta-secretase. The sequence recognized by this corresponds to amino acids 85-99 of the C99 fragment. The C99 fragment itself is a substrate for gamma-secretase to generate the 4 kD beta amyloid peptide, found in the brains of Alzheimer's disease patients. APP also inhibits Notch signaling through it's i
- Storage Conditions:
- 2[o]C to 8[o]C or -20[o]C Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:42558
