APAF1 / APAF-1 Antibody (aa12-28)
Product Sizes
0.1 mg
£ POA
LS-C42802-0.1MG
About this Product
- SKU:
- LS-C42802
- Additional Names:
- APAF1, APAF-1, CED4, KIAA0413
- Application:
- IHC-Paraffin, Immunohistochemistry, Western Blot
- Buffer:
- PBS, 0.02% Sodium Azide
- Clonality:
- Polyclonal
- Concentration:
- 1 mg/ml
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to amino acids 12-28 of human Apaf1 (AA 12-28).
- Isotype:
- IgG
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade characteristic of apoptosis. Apaf1 can also associate with caspase-4 and caspase-8. AHP487 recognizes a 130kD band in Western blots.
- Storage Conditions:
- 2[o]C to 8[o]C or -20[o]C Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:42540
