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Product Sizes
0.1 mg
£ POA
LS-C413712-0.1MG
About this Product
SKU:
LS-C413712
Additional Names:
APC, Adenomatosis polyposis coli, Adenomatous polyposis coli, BTPS2, Deleted in polyposis 2.5, DP2, DP2.5, FPC, GS, Protein APC, PPP1R46, DP3
Application:
ELISA, Western Blot
Buffer:
PBS, pH 7.4, 0.09% sodium azide, 15% glycerol.
Clonality:
Polyclonal
Host:
Rabbit
Immunogen:
KLH-conjugated synthetic peptide from the N-Terminus of human APC.
Purification:
Protein A Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Ambient
Specificity:
The adenomatous polyposis coli protein (APC) is a tumor suppressor that promotes rapid degradation of catenin-beta 1 (CTNNB1) and participates in Wnt signaling. The GSK3-beta protein kinase regulates its activity by phosphorylation. APC binds to PDZ domains of DLG1 and 3, to catenins, axin and MAPRE protein family including the EB members.
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
LifeSpan Biosciences
Type:
Antibody: Polyclonal Antibody
  • Manufacturer's Data Sheet:426147
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