LIME1 / LIME Antibody (aa281-296, clone LIME-10, Concentrated)
Product Sizes
0.1 mg
£ POA
LS-C204122-0.1MG
About this Product
- SKU:
- LS-C204122
- Additional Names:
- LIME1, DJ583P15.4, Lck-interacting molecule, LIME, RP4-583P15.5, LP8067
- Application:
- Western Blot
- Buffer:
- PBS, pH 7.4, 15 mM Sodium Azide
- translate.label.attr.clone:
- LIME-10
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Host:
- Mouse
- Immunogen:
- COOH-terminal peptide comprising residues 281-296 of the human LIME conjugated to keyhole limpet hemocyanin
- Isotype:
- IgG2a
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- LIME (Lck-interacting molecule) is a new raft-associated adaptor protein involved in regulation of T cell activation by coreceptors. LIME becomes tyrosine phosphorylated after cross-linking of the CD4 or CD8 coreceptors. Phospho-LIME associates with the Src family kinase Lck and its negative regulator, Csk. Ectopic expression of LIME in Jurkat T cells results in an increase of Csk in lipid rafts,
- Storage Conditions:
- 2-8[o]C
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:212378
