SOS1 Antibody (clone SOS-01)
Product Sizes
0.1 mg
£ POA
LS-C188432-0.1MG
About this Product
- SKU:
- LS-C188432
- Additional Names:
- SOS1, GINGF, NS4, SOS-1, Son of sevenless homolog 1, GF1, GGF1
- Application:
- ELISA, Immunofluorescence, Western Blot
- Buffer:
- PBS, 0.09% Sodium Azide
- translate.label.attr.clone:
- SOS-01
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Host:
- Mouse
- Immunogen:
- Synthetic peptide corresponding to amino acids THPSMHRDGPPLLENAHSS of human SOS1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Ferret, Elephant, Panda, Bovine, Cat, Horse, Rabbit, Opossum, Guinea pig (100%); Dog, Turkey, Zebra finch (95%); Lizard (89%).
- Isotype:
- IgG1
- Purification:
- Protein A Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- Recognizes SOS1 (son of sevenless homolog 1), a ubiquitously expressed 150kD intracellular protein and bifunctional guanine nucleotide exchange factor (GEF), which plays a role in growth and differentiation signalling pathways and in actin reorganization, by acting as a regulator of Ras and Rac/Rho GTPases. Mutations in the SOS1 gene are responsible for the rare oral overgrowth condition known as
- Storage Conditions:
- 2[o]C to 8[o]C or -20[o]C Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:196335
