CD3E Antibody (clone APA1/1)
Product Sizes
0.1 mg
£ POA
LS-C112447-0.1MG
About this Product
- SKU:
- LS-C112447
- Additional Names:
- CD3E, CD3e antigen, CD3-epsilon, T-cell receptor epsilon chain, TCRE, T-cell receptors epsilon chain, T3E, CD3 Epsilon, CD3
- Application:
- Flow Cytometry, IHC-Frozen, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS, pH 7.4, 15 mM Sodium Azide
- translate.label.attr.clone:
- APA1/1
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Host:
- Mouse
- Immunogen:
- Purified human CD3 proteins isolated from thymus.
- Isotype:
- IgG1
- Purity:
- >95%
- Purification:
- Protein A Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Ambient
- Specificity:
- The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Monoclonal Antibody
- Manufacturer's Data Sheet:114970
