IHC-plus[TM] MDM2 Antibody (aa154-167, clone SMP14)
Product Sizes
50 ug
LS-B163-50UG
About this Product
- SKU:
- LS-B163
- Additional Names:
- MDM2, ACTFS, Double minute 2 protein, Hdm2, MDM2 variant FB30, HDMX, Oncoprotein Mdm2, p53-binding protein Mdm2, MDM2 variant FB28
- Application:
- IHC-Frozen, IHC-Paraffin, Immunohistochemistry
- Buffer:
- PBS, 0.09% Sodium Azide
- translate.label.attr.clone:
- SMP14
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Host:
- Mouse
- Immunogen:
- Synthetic peptide, CSRPSTSSRRRAISE, corresponding to amino acids 154-167 of human MDM2. Percent identity by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Marmoset, Rat, Dog, Panda (100%); Bat, Cat, Bovine, Hamster, Elephant, Horse, Pig (93%); Mouse (86%).
- Isotype:
- IgG1
- Purification:
- Purified
- Reactivities:
- Human
- Shipping Conditions:
- Ambient
- Specificity:
- Recognizes the 90kD MDM2 protein, which forms a complex with p53 leading to p53 inhibition. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. MDM2 is over expressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer.
- Storage Conditions:
- 2[o]C to 8[o]C or -20[o]C Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Monoclonal Antibody
- 2B Price Match:
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- Free UK Delivery:
- Standard UK Delivery is free for orders over £100
- Manufacturer's Data Sheet:28084
