IHC-plus[TM] FKBP38 / FKBP8 Antibody
Product Sizes
50 ug
LS-B15749-50UG
About this Product
- SKU:
- LS-B15749
- Additional Names:
- FKBP8, 38 kDa FKBP, 38 kDa FK506-binding protein, FKBP-8, FK506-binding protein 8, FKBP38, HFKBP38, FKBP-38, Rotamase, FK506 binding protein 8, 38kDa, FK506-binding protein 8 (38kD), FKBPr38, PPIase FKBP8
- Application:
- ELISA, IHC-Paraffin, Immunohistochemistry, Western Blot
- Buffer:
- PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
- Clonality:
- Polyclonal
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP8 protein (58-190AA)
- Isotype:
- IgG
- Purification:
- Protein G Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Ambient
- Specificity:
- Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
- Storage Conditions:
- -70[o]C Avoid freeze/thaw cycles.
- Supplier:
- LifeSpan Biosciences
- Type:
- Antibody: Polyclonal Antibody
- 2B Price Match:
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- Free UK Delivery:
- Standard UK Delivery is free for orders over £100
- Manufacturer's Data Sheet:709069
