E6AP
Product Sizes
25 ug
£629.00
UB-0304-0025-25UG
About this Product
- SKU:
- UB-0304-0025
- Application:
- Cell-based/Functional Assay
- Extra Details:
- E6-AP (E6-associated protein) is an E3 (ubiquitin protein ligase) that is involved in the conjugation of ubiquitin to target substrates along with E1 and E2 enzymes. It is a HECT domain E3 containing an active site cysteine that accepts a charged ubiquitin from the ubiquitin-E2 thioester complex. E6-AP has been linked to the neurodevelopmental disorder, Angelman syndrome. Additionally, the oncoprotein E6 of human papillomaviruses (HPV) utilizes E6-AP to target numerous cellular proteins for degradation including the tumor suppressor protein p53.
- Shipping Conditions:
- Dry Ice
- Storage Conditions:
- -70[o]C
- Supplier:
- LifeSensors
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
- Manufacturer's Data Sheet:https://lifesensors.com/product/ub304-e6ap/