Nutlin-3
Product Sizes
5 mg
£396.00
SI-9870-0005-5MG
About this Product
- SKU:
- SI-9870-0005
- Application:
- Cell-based/Functional Assay
- CAS Number:
- 548472-68-0
- Extra Details:
- Cis-imidazoline analog that inhibits the interaction between p53 and its negative regulator MDM2 (IC50 = 0.09 uM). It induces the expression of p53-regulated genes and exhibits potent antiproliferative activity in cells with functional p53, but not in cells with mutated p53. Nutlin-3 also inhibits the growth of human tumor xenografts in nude mice by 90% at a dose of 200 mg/kg.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- LifeSensors
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
