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Proteins and Peptides

Tenovin 1

Product Sizes
10 mg
£290.00
SI-9865-0010-10MG
About this Product
SKU:
SI-9865-0010
Application:
Cell-based/Functional Assay
CAS Number:
380315-80-0
Extra Details:
Tenovin 1 inhibits the deacetylase activity of SirT1 and SirT2. One of the substrates for SirT1 is p53 which is stabilized by acetylation of Lys-382. The ability of p53 to bind DNA is also enhanced by acetylation of Lys-382. Hence, inhibition of SirT1 by tenovin 1 leads to increased stability and activity of p53.
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
LifeSensors
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors