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Proteins and Peptides

PS-341

Product Sizes
25 mg
SI-9720-0025-25MG
About this Product
SKU:
SI-9720-0025
Application:
Cell-based/Functional Assay
CAS Number:
179324-69-7
Extra Details:
PS-341 (Pyz-Phe-boroLeu) is the active ingredient in Bortezomib (Velcade). PS-341 is a reversible, cell-permeable, potent, and selective proteasome inhibitor (Ki = 0.6 nM). It binds the catalytic site of the 26S proteasome with high affinity and specificity. Inhibits proliferation of a number of tumor cell lines (IC50 = 7 nM). Inhibits TNF synthesis and FGF-induced angiogenesis.
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Supplier:
LifeSensors
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors