MG-132, proteasome inhibitor
Product Sizes
25 mg
£622.00
SI-9710-0025-25MG
About this Product
- SKU:
- SI-9710-0025
- Application:
- Cell-based/Functional Assay
- CAS Number:
- 133407-82-6
- Extra Details:
- MG-132 is a potent, cell-permeable inhibitor of the proteasome (IC50=0.1 uM) and calpain (IC50=1.2 uM). MG-132 inhibits TNF-A Alpha-induced NF-K KappaB activation and IK KappaBA Alpha degradation (IC50=3 uM). MG-132 reduces the degradation of ubiquitin-conjugated proteins in different cell types and promotes apoptosis via activation of c-Jun N-terminal kinase (JNK1).
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- LifeSensors
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
