P22077 Inhibitor
Product Sizes
50 mg
£718.00
SI-9699-0050-50MG
About this Product
- SKU:
- SI-9699-0050
- Application:
- Cell-based/Functional Assay
- CAS Number:
- 1247819-59-5
- Extra Details:
- P22077 is a cell-permeable inhibitor of the ubiquitin-specific protease USP7 (IC50 = 8.6 uM), and the closely related deubiquitinase (DUB) USP47. P22077 showed weak or no inhibition (EC50 > 50 uM) towards a panel of 14 isopeptidases and other proteases. Treatment of cells with P22077 (20-40 uM) causes an accumulation of K48-linked ubiquitinated species, and downregulation of the USP7 targets HDM2 and claspin.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- LifeSensors
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
