Spautin 1
Product Sizes
5 mg
£265.00
SI-9644-0005-5MG
About this Product
- SKU:
- SI-9644-0005
- Application:
- Cell-based/Functional Assay
- CAS Number:
- 126288-28-7
- Extra Details:
- Spautin 1 inhibits USP10 and USP13 with IC50's of 0.6 uM and 0.7 uM, respectively. These deubiquitylases target the Beclin-1 subunit and promote degradation of Vps34-PI3 kinase complexes. Its effect on autophagy is Beclin-independent. Spautin induces apoptosis of cancer cells under starvation conditions.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- LifeSensors
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
