LDN-57444, DUB inhibitor
Product Sizes
10 mg
£326.00
SI-9639-0010-10MG
About this Product
- SKU:
- SI-9639-0010
- Application:
- Cell-based/Functional Assay
- CAS Number:
- 668467-91-2
- Extra Details:
- LDN-57444 is a cell permeable ubiquitin C-terminal hydrolase (UCH-L1) inhibitor (Ki=0.4 uM) with approximately 28-fold greater selectivity over UCH-L3. Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis and causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. LDN-57444 is a useful tool to study UCH-L1 in different pathological conditions such as cancer and neurodegeneration.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- LifeSensors
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
