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Proteins and Peptides

Single Lysine Ubiquitin Explorer Panel

Product Sizes
1 mg
£907.00
SI-0210-0000-1MG
About this Product
SKU:
SI-0210-0000
Additional Names:
HMG20;polyubiquitin-C
Application:
Cell-based/Functional Assay
Extra Details:
Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to the primary amine groups of a lysine residue on target proteins. This covalent attachment is referred to as monoubiquitylation. Additional ubiquitin moieties can subsequently be conjugated to this initial ubiquitin, utilizing any one (of seven) lysine residue on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation. LifeSensors has produced a complete panel of tag-free recombinant human ubiquitins that are engineered to have all available lysines mutated to arginines except at position mentioned. For example, ubiquitin-K6 has all available lysines mutated to arginines except at position 6, such that this molecule can only form polyubiquitin chains of K6-linkage type. The panel consists Ub mutants- K6, K11, K27, K29, K33, K48, and K63. The panel also contains WT Ub and ubiquitin-K0 (all lysines mutated to arginines).
Gene Details:
UBC
Protein Details:
P0CG48
Shipping Conditions:
Dry Ice
Storage Conditions:
2-8[o]C
Supplier:
LifeSensors
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins