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Proteins and Peptides

USP14

Product Sizes
25 ug
£296.00
DB-0505-0025-25UG
About this Product
SKU:
DB-0505-0025
Application:
Cell-based/Functional Assay
Extra Details:
USP14 (Ubiquitin Specific Protease 14) is a proteasome-associated deubiquitinase which releases ubiquitin from the proteasome-targeted ubiquitinated proteins. This enzyme serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded ER proteins via interaction with ERN1. It also plays a role in the innate immune defense against viruses by stabilizing the viral DNA sensor CGAS and thus inhibiting its autophagic degradation.
Shipping Conditions:
Dry Ice
Storage Conditions:
-70[o]C
Supplier:
LifeSensors
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes