Xanthohumol
Product Sizes
5 mg
£303.00
AC-1008-0005-5MG
About this Product
- SKU:
- AC-1008-0005
- Application:
- Cell-based/Functional Assay
- CAS Number:
- 6754-58-1
- Extra Details:
- Xanthohumol binds to the N-terminal domain of valosin-containing protein (VCP), an essential protein for autophagosome maturation. Xanthohumol inhibits the function of VCP thereby impairing autophagosome maturation resulting in accumulation of the microtubule-associated protein 1 light chain 3-II (LC3-II). It also impairs prostate cancer cell growth and proliferation. Xanthohumol suppresses the growth of pancreatic cancer cells via down-regulation of Notch1 signaling. Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- LifeSensors
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
