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Proteins and Peptides

Chloroquine diphosphate

Product Sizes
Chloroquine diphosphate
£242.00
AC-1003-0025
Academic Pricing
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About this Product
SKU:
AC-1003-0025
Application:
Cell-based/Functional Assay
CAS Number:
50-63-5
Extra Details:
Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. It inhibits autophagy in a variety of cell lines, induces cell death in breast cancer cell lines, and displays antitumor and antimetastatic activity in mouse models of breast cancer. Chloroquine diphosphate eliminates cancer stem cells via deregulation of Jak2 and DNMT1. It displays synergy when combined with the Raf inhibitor, vemurafenib, in brain tumors. It is also cell permeable and active in vivo.
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Size:
25 mg
Supplier:
LifeSensors
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules