anti-Pam-Igloo-L, anti Periplaneta Americana Igloo L 1-75, rabbit, polyclonal
Product Sizes
100 ul
£254.00
ABD-060-100UL
About this Product
- SKU:
- ABD-060
- Application:
- ELISA, Immunocytochemistry
- Extra Details:
- Axogenesis and synaptic signal transmission in the vertebrate nervous system are based on the abundant expression of the growth-associated protein GAP-43. In non-vertebrates a GAP-43 related gene (igloo, invertebrate GAP-43 like) was found in Drosophila and encodes two proteins, IGLOO-L and IGLOO-S, with sequence homology and similar biochemical activity to GAP-43. We have cloned a GAP-43-like gene in a holometabolic insect, the American cockroach, Periplaneta americana. As for Drosophila, we found two putative pigl mRNAs, pigl-L and pigl-S, in the cockroach (Fig. 1). Immunocytochemical investigations with a antiserum to Pam-Igl L and Pam-Igl S provide a function for Pam-Igloo L in establishment or maintenance of synaptic contacts and can help to understand the ongoing expression of GAP-43 in the mature nervous system (Haenold,2004).
- Physical State:
- Liquid
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Jena Bioscience
- Type:
- Antibody
