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Proteins and Peptides

Phospho glycogen synthase peptide 2

Product Sizes
1 mg
£200.00
SP-030-1MG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
SP-030
Additional Names:
GS peptide 2|Phospho Glycogen Synthase Peptide 2 (substrate), GS peptide-2, 851366-97-7, YRRAAVPPSPSLSRHSSPHQS(OPO3H2)EDEEE, YRRAAVPPSPSLSRHSSPHQSEDEEE, SP-030, SP030
CAS Number:
851366-97-7
Extra Details:
Phospho glycogen synthase peptide 2 is a synthetic peptide substrate for glycogen synthase kinase 3 (GSK 3). Phospho glycogen synthase peptide 2 when immobolised can be used for affinity purification of protein-serine kinases. Phospho glycogen synthase peptide 2 can also be used to inhibit the human dual specificity protein kinase CLK2.
Immunogen:
Kinases
Molecular Weight:
3029
Physical State:
Freeze dried solid
Purity:
>95%
References:
<p>Woodgett (1989) Use of peptide substrates for affinity purification of protein-serine kinases. Anal.Biochem. <strong>180</strong> 237 <a href="https://pubmed.ncbi.nlm.nih.gov/2554753/" target="_blank" rel="nofollow">PMID: 2554753</a></p><p>Sutherland et al (1993) Inactivation of glycogen synthase kinase-3β by phosphorylation: new kinase connections in Ins and growth factor signalling. Biochem.J. <strong>296</strong> 15 <a href="https://pubmed.ncbi.nlm.nih.gov/8250835/" target="_blank" rel="nofollow">PMID: 8250835</a></p><p>Tanji et al (2002) A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta. J Biol Chem. <strong>277</strong>(40):36955 <a href="https://pubmed.ncbi.nlm.nih.gov/12147701/" target="_blank">PMID: 12147701</a></p><p><a href="https://pubchem.ncbi.nlm.nih.gov/bioassay/1436446" target="_blank" rel="nofollow">Inhibition of human CLK2 using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate</a></p>
Sequence:
H-Tyr-Arg-Arg-Ala-Ala-Val-Pro-Pro-Ser-Pro-Ser-Leu-Ser-Arg-His-Ser-Ser-Pro-His-Gln-Ser(OPO3H2)-Glu-Asp-Glu-Glu-Glu-OH
Shipping Conditions:
Blue Ice
Storage Conditions:
Store dry, frozen and in the dark
Size:
1 mg
Supplier:
Isca Biochemicals
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
Solubility:
Soluble to 1 mg/ml in water
Formula:
C123H191N40O48P