QK
Product Sizes
1 mg
£165.00
RT-040-1MG
About this Product
- SKU:
- RT-040
- Additional Names:
- Ac-KLTWQELYQLKYKGI-NH2, RT-040, RT040, QK, KLT, PQK|KLT, QK peptide, PQK
- Extra Details:
- QK is a peptide derived from the 17-25 A Alpha-helical region of vascular endothelial growth factor (VEGF), which is the region of VEGF involved when binding to its receptor Flt-1 (VEGFR-1), QK acts as a VEGF mimetic and agonist and can reproduce the biological activity of VEGF while retaining its bioactivity much longer in vivo than the full-length protein. QK promotes proliferation and angiogenic differentiation of endothelial cells and can promote microvascularization in vitro and in vivo. QK can be used as a VEGF mimetic agent in reparative angiogenesis and has been synthesised as a nanoparticle for enhanced stability, in this form it has been used to prevent the occurrence of bisphosphonate-related osteonecrosis of the jaw (BRONJ).
- Immunogen:
- Receptor tyrosine kinases
- Molecular Weight:
- 1951.09
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- Sequence:
- Ac-Lys-Leu-Thr-Trp-Gln-Glu-Leu-Tyr-Gln-Leu-Lys-Tyr-Lys-Gly-Ile-NH2
- Shipping Conditions:
- Blue Ice
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
