A 83-01
Product Sizes
5 mg
£118.00
RK-020-5MG
About this Product
- SKU:
- RK-020
- Additional Names:
- A 83-01, RK-020, RK020, 909910-43-6
- CAS Number:
- 909910-43-6
- Extra Details:
- A 83-01 is a potent inhibitor of TGF-B Beta type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7, with IC50 values of 12, 45 and 7.5 nM respectively, and only weak inhibition of ALK-1, -2, -3, -6 and MAPK. A 83-01 inhibits differentiation of rat induced pluripotent stem cells (riPSCs) and increases clonal expansion efficiency. A 83-01 helps maintain homogeneity and long-term in vitro self-renewal of human induced pluripotent stem cells (hPSCs) and also promotes neural differentiation of hPSCs as part of a chemical cocktail.
- Immunogen:
- Receptor serine/threonine kinase receptors
- Molecular Weight:
- 421.53
- Physical State:
- Solid
- Purity:
- 98% by TLC, NMR conforms
- Sequence:
- 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
- Shipping Conditions:
- Blue Ice
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
