B Beta-5
About this Product
- SKU:
- PT-110
- Additional Names:
- Beta-5|Beta-5, B Beta-5, Ntri-NLys(Me)3-Ntma, PT-110, lipopeptoid, antifungal
- Extra Details:
- B Beta-5 is a trimeric lipopeptoid with antifungal activity against Cryptococcus neoformans and minimal mammalian cell toxicity. B Beta^'5 is an optimized derivation of AEC5 and has improved potency towards C. neoformans and decreased toxicity towards NIH/3T3 mouse fibroblasts, with a selectivity ratio improved from 8 for AEC5 to 37 for B Beta^'5.
- Immunogen:
- Antifungals
- Molecular Weight:
- 580.9
- Physical State:
- Freeze dried solid
- Purity:
- 93.3% by hplc
- References:
- Middleton et al (2018) Improved Potency and Reduced Toxicity of the Antifungal Peptoid AEC5 Through Submonomer Modification. Bioorg. Med. Chem. Lett. <strong>28</strong>(22) 3514 <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246776/" target="_blank">PMID: 30297282</a>
- Sequence:
- Ntri-NLys(Me)3-Ntma
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- >50 mg per ml in water
- Formula:
- C31H58N5O3S+
