Caveolin-1 scaffolding domain peptide
About this Product
- SKU:
- PP-170
- Additional Names:
- Caveolin-1 Scaffolding Domain Peptide, Caveolin 1 Scaffolding Domain Peptide, CSD, DGIWKASFTTFTVTKYWFYR-NH2, PP-170, PP170|CSD
- Extra Details:
- Caveolin-1 scaffolding domain peptide is amino acids 82-101 of caveolin-1, a structural cytoplasmic membrane protein involved in the formation and function of caveolae. Caveolin-1 scaffolding domain peptide can reverse aging associated fibrosis, microvascular leakage, and organ dysfunction in the heart, kidneys, and brain of mice through a mechanism that involves the suppression of the activity of multiple tyrosine kinases, reducing age related microvascular leakage and interstitial fibrosis to the levels of healthy, young mice.
- Immunogen:
- Protein-protein interactions,Kinases
- Molecular Weight:
- 2516.88
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- Kuppuswamy et al (2021) The Caveolin-1 Scaffolding Domain Peptide Reverses Aging-Associated Deleterious Changes in Multiple Organs. J Pharmacol Exp Ther. <strong>378</strong>(1) 1 <a href="https://pubmed.ncbi.nlm.nih.gov/33879542/" target="_blank" rel="nofollow">PMID: 33879542</a>
- Sequence:
- H-Asp-Gly-Ile-Trp-Lys-Ala-Ser-Phe-Thr-Thr-Phe-Thr-Val-Thr-Lys-Tyr-Trp-Phe-Tyr-Arg-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in DMSO
- Formula:
- C124 H170N28O29
