TAT-AKAP79 (326-336)
About this Product
- SKU:
- PP-130
- Additional Names:
- TAT-AKAP79 (326-336), H-YGRKKRRQRRRKSKSEESKRME-OH, YGRKKRRQRRRKSKSEESKRME, A-kinase anchoring protein 79, AKAP79, transient receptor potential vanilloid 1 , TRPV1, hyperalgesia in mice, PP-130
- Extra Details:
- TAT-AKAP79 (326-336) is amino acids 326-336 of A-kinase anchoring protein 79 (AKAP79), the human anchoring protein, fused to TAT to promote uptake across the cell membrane. AKAP79 (326-336) is the the key region of AKAP79 for interaction with transient receptor potential vanilloid 1 (TRPV1), the thermo-TRP ion channel activated by painful levels of heat, and AKAP79 binding to TRPV1 blocks TRPV1 sensitization. TAT-AKAP79 (326-336) inhibits inflammatory hyperalgesia in mice.
- Immunogen:
- Protein-protein interactions,Transient receptor potential (TRP) channels
- Molecular Weight:
- 2880.34
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- Btesh et al (2014) Mapping the Binding Site of TRPV1 on AKAP79: Implications for Inflammatory Hyperalgesia. J Neurosci. <strong>33</strong>(21) 9184 DOI: 10.1523/JNEUROSCI.4991-12.2013
- Sequence:
- H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Ser-Lys-Ser-Glu-Glu-Ser-Lys-Arg-Met-Glu-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in DMSO
- Formula:
- C117H211N49O34S1
