KSL 128114
Product Sizes
KSL 128114
£259.00
PP-030
About this Product
- SKU:
- PP-030
- Extra Details:
- KSL 128114 is a potent, and metabolically stable peptide inhibitor of syntenin, which binds the PDZ1 domain of syntenin with nanomolar affinity. KSL 128114 is resistant toward degradation in human plasma and mouse hepatic microsomes and shows an inhibitory effect on primary glioblastoma cell viability. KSL 128114 significantly extends survival time in a patient derived glioblastoma xenograft mouse model.
- Molecular Weight:
- 2201.6
- Purity:
- >95%
- References:
- Haugaard-Kedström et al (2021) A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma. J.Med.Chem. <strong>64</strong> 1423
- Sequence:
- Ac-arg-Arg-arg-Gly-arg-Lys-lys-Arg-arg-Ser-His-Trp-Tle-Chg-Asp-Ile-OH
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in water
- Formula:
- C94H163N39O20