H10, biotinylated
About this Product
- SKU:
- PP-010
- Additional Names:
- H10, biotinylated, Biotin-GGGSGMKMQVRIYLV-OH, GGGSGMKMQVRIYLV, PP-010
- Conjugate:
- Biotin
- Extra Details:
- H10, biotinylated is the N-terminal biotinylated version of the anterior gradient 2 (AGR2) binding peptide H10 (MKMQVRIYLV) which was identified by mRNA display from a complex (>1011) library. AGR2 is a cancer-associated protein and increased levels of extracellular AGR2 (eAGR2) have been correlated with poor prognosis in cancer patients, making it a potential biomarker. H10 possesses high affinity binding to AGR2 with a KD of 6.4 nM, and has been used as the capture reagent in an AGR2 ELISA. H10 can also inhibit cancer cell migration in breast and prostate cancer cell lines.
- Immunogen:
- Protein-protein interactions
- Molecular Weight:
- 1822.26
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- Garri et al (2018) Identification, characterization and application of a new peptide against anterior gradient homolog 2 (AGR2). Oncotarget<strong> 9</strong>(44) 27363-27379 doi: 10.18632/oncotarget.25221. PMID: 29937991
- Sequence:
- Biotin-Gly-Gly-Gly-Ser-Gly-Met-Lys-Met-Gln-Val-Arg-Ile-Tyr-Leu-Val-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in water
- Formula:
- C79H132N22O21S3
