TCID
Product Sizes
10 mg
£95.00
PI-200-10MG
About this Product
- SKU:
- PI-200
- Additional Names:
- TCID, ubiquitin C-terminal hydrolase-L3, UCH-L3, 30675-13-9
- CAS Number:
- 30675-13-9
- Extra Details:
- TCID is a selective ubiquitin C-terminal hydrolase-L3 (UCH-L3) inhibitor with an IC50 of 0.6 uM. TCID exhibits >100-fold selectivity for UCH-L3 over UCH-L1. TCID can also diminish glycine transporter GlyT2 ubiquitination in brain stem and spinal cord primary neurons.
- Immunogen:
- Deubiquitinating enzymes
- Molecular Weight:
- 283.91
- Physical State:
- Solid
- Purity:
- %99% (HPLC)
- References:
- <p>Liu et al (2003) Discovery of inhibitors that elucidate the role of UCH-L1 activity in the H1299 lung cancer cell line. Chem.Biol. <strong>10</strong> 837 PMID: 14522054 </p><p>de Juan-Sanz et al (2013) Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster. PLoS ONE <strong>8</strong> e58863 PMID: 23484054</p>
- Sequence:
- 4,5,6,7-Tetrachloro-1H-Indene-1,3(2H)-dione
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 10 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Solubility:
- Soluble in DMSO
- Formula:
- C9H2Cl4O2
