Z-Phe-CMK
About this Product
- SKU:
- PI-190
- Additional Names:
- 26049-94-5, Z-Phe-CMK,SL-01, ZPCK, chymotrypsin, carboxypeptidase Y, PI-190, PI190|SL-01, ZPCK
- CAS Number:
- 26049-94-5
- Extra Details:
- Z-Phe-CMK, also known as SL-01 and ZPCK, is a chymotrypsin inhibitor. Z-Phe-CMK has been shown to inhibit both peptidase and esterase activities of carboxypeptidase Y from baker's yeast.
- Immunogen:
- Serine proteases
- Molecular Weight:
- 331.8
- Physical State:
- Solid
- Purity:
- >95% by tlc
- References:
- <p>Segal et al (1971) Substrate binding site in bovine chymotrypsin A-gamma. A crystallographic study using peptide chloromethyl ketones as site-specific inhibitors. Biochemistry <strong>10</strong>(20) 3728 doi:10.1021/bi00796a014 </p><p>Hayashi et al (1975) Evidence for an essential histidine in carboxypeptidase Y. Reaction with the chloromethyl ketone derivative of benzyloxycarbonyl-L-phenylalanine. J. Biol. Chem. <strong>250</strong>(13) 5221 </p><p> Volbracht et al (2001) Apoptosis in caspase-inhibited neurons. Mol. Med. <strong>7</strong>(1) 36</p>
- Sequence:
- N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-carbamic acid-phenylmethyl ester
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 5 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Solubility:
- Soluble in DMSO and ethanol
- Formula:
- C18H18ClNO3
