Puromycin dihydrochloride
Product Sizes
50 mg
£83.00
PI-160-50MG
About this Product
- SKU:
- PI-160
- Additional Names:
- Puromycin, antibiotic, dipeptidyl-peptidase II, serine peptidase, aminopeptidase, metallopeptidase, cell biology, 58-58-2, PI-160, PI160
- CAS Number:
- 58-58-2
- Extra Details:
- Puromycin is a broad spectrum antibiotic and protein synthesis inhibitor produced by Streptomyces alboniger, active in both prokaryotes and eukaryotes. Puromycin is a reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase (metallopeptidase). Puromycin is used in cell biology as a selective agent in cell culture systems.
- Immunogen:
- Other proteases,Antibacterials
- Molecular Weight:
- 544.43
- Physical State:
- Solid
- Purity:
- %98% (HPLC)
- References:
- <p>Azzam and Algranati (1973) Mechanism of puromycin action: fate of ribosomes after release of nascent polypeptide chains from polysomes. Proc.Nat.Acad.Sci. <strong>70</strong> 3866 </p><p>Price and Verner (1993) Puromycin inhibits protein import into mitochondria by interfering with an intramitochondrial ATP-dependent reaction. Biochim.Biophys.Acta. <strong>1150</strong> 89 PMID: 8334141 </p><p>Matsumoto and Saitoh H (2016) Puromycin induces SUMO and ubiquitin redistribution upon proteasome inhibition. Biochem. Biophys. Res. Comm. <strong>476</strong>(3) 153 DOI: 10.1016/j.bbrc.2016.05.025.</p>
- Sequence:
- 3'-[A Alpha-Amino-p-methoxyhydrocinnamamido]-3'-deoxy-N,N-dimethyladenosine dihydrochloride
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 50 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Solubility:
- Soluble in water
- Formula:
- C22H29N7O5.2HCl
