NSC 632839
Product Sizes
10 mg
£95.00
PI-080-10MG
About this Product
- SKU:
- PI-080
- Additional Names:
- 157654-67-6, NSC 632839, F6, ubiquitin-proteasome, ubiquitin isopeptidases, apoptosome-independent, death receptor, PI-080, PI080|F6
- CAS Number:
- 157654-67-6
- Extra Details:
- NSC 632839, also known as F6, targets the ubiquitin-proteasome system by inhibiting ubiquitin isopeptidases. NSC 632839 is able to activate an apoptosome-independent apoptotic pathway which includes a Bcl-2-dependent but apoptosome-independent mitochondrial pathway with up-regulation of the BH3-only protein Noxa, stabilization of the inhibitor of apoptosis antagonist Smac, and also the involvement of the death receptor pathway
- Immunogen:
- Deubiquitinating enzymes
- Molecular Weight:
- 339.86
- Physical State:
- Solid
- Purity:
- >98% by tlc
- References:
- Aleo et al (2006) Identification of New Compounds That Trigger Apoptosome-Independent Caspase Activation and Apoptosis. Cancer Res. <strong>66</strong>(18) 9235 DOI: 10.1158/0008-5472.CAN-06-0702
- Sequence:
- 3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Stotre, dry, frozen and in the dark
- Size:
- 10 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Solubility:
- Soluble in water
- Formula:
- C21H21NO.HCl
