N-Ethylmaleimide
Product Sizes
N-Ethylmaleimide
PI-050
About this Product
- SKU:
- PI-050
- CAS Number:
- 128-53-0
- Extra Details:
- N-Ethylmaleimide is a sulfhydryl alkylating reagent which has been used for blocking sulfhydryl containing reagents which interfere with glucose oxidase assays. N-Ethylmaleimide inactivates NADP-dependent isocitrate dehydrogenase and is also an endonuclease inhibitor. N-Ethylmaleimide is also a potent inhibitor of both Mg2+ and Ca2+/Mg2+-stimulated DNA fragmentation in rat liver nuclei.
- Molecular Weight:
- 125.13
- Purity:
- >98% by HPLC
- References:
- <p>Huang et al (1995) N-ethylmaleimide profiling of yeast NADP-dependent isocitrate dehydrogenase. Arch. Biochem. Biophys. <strong>316(</strong>1) 485 doi:10.1006/abbi.1995.1064 </p><p>Lain et al (1994) Dependence of the folding and import of the precursor to mitochondrial aspartate aminotransferase on the nature of the cell-free translation system. J. Biol. Chem.<strong> 269</strong>(22) 15588 </p><p>Zhao and Brunger (2016) Recent Advances in Deciphering the Structure and Molecular Mechanism of the AAA+ ATPase N-Ethylmaleimide-Sensitive Factor (NSF). J. Mol. Biol. <strong>428</strong> (9 Part B) 1912 https://doi.org/10.1016/j.jmb.2015.10.026.</p>
- Sequence:
- 1-Ethyl-1H-pyrrole-2,5-dione
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 g
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in ethananol
- Formula:
- C6H7NO2
